ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7

Published monthly
 

Synthesis of some substituted tetrazolylacetic acids

Ľ. Janda and Z. Votický

Drug Research Institute, CS-900 01 Modra

 

Abstract: Alkylation of 5-(5-bromo-2-furyl)-l#-tetrazole with ethyl bromoacetate afforded a mixture of ethyl 5-(5-bromo-2-furyl)-l-tetrazolylacetate and ethyl 5-(5-bromo-2-furyl)-2-tetrazolylacetate; these were chromatographically separated and the ester substituted in position 1 was the substrate for the nucleophilic substitution with 4-substituted thiophenols. The resulting ethyl 5-[5-(4-R-phenylthio)-2-furyl]-l-tetrazolylacetates were hydrolyzed to corresponding acids.

Full paper in Portable Document Format: 431a63.pdf

 

Chemical Papers 43 (1) 63–71 (1989)

Thursday, March 28, 2024

IMPACT FACTOR 2021
2.146
SCImago Journal Rank 2021
0.365
SEARCH
Advanced
VOLUMES
European Symposium on Analytical Spectrometry ESAS 2022
© 2024 Chemical Papers