ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Reactions of saccharides catalyzed by molybdate ions. XXXIII. Use of α-[U-¹⁴C]glucan for preparation of ¹⁴C-labeled saccharides

V. Bílik, P. Biely, and J. Kolina

Institute of Chemistry, Centre for Chemical Research, Slovak Academy of Sciences, CS-842 38 Bratislava

Abstract:  D-[U-¹⁴C]Glucose obtained on acid hydrolysis of a-[U- ¹⁴C]glucan (2 M-HCl) is epimerized under a catalytic action of molybdate ions to D-[U- ¹⁴C]mannose isolated in 20 % iyeld. Oxidative degradation of 4-nitrophenylhydrazones of D-[U-¹⁴C]arabinose and D-[U-¹⁴C]xylose affords D-[U-¹⁴C]erythrose and D-[U-¹⁴C]threose, respectively, in 15 % yield when referred to the starting aldopentoses. Nitromethane synthesis with D-[U-¹⁴C]lyxose followed by oxidative decomposition of the corresponding nitrohexitols gives ¹⁴C-labelled D-galactose. Described is also the preparation of D-[U-¹⁴C]arabinose from D-[U-¹⁴C]glucose and the conversion of D-[U-¹⁴C]arabinose to D-[U-¹⁴C]xylose and D-[U-14C]lyxose.

Full paper in Portable Document Format: 384a491.pdf

Chemical Papers 38 (4) 491–498 (1984)