ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Novel n-octadecylcarboxamide CoPc: amperometric detections for bioanalytes using modified GCE

Mounesh, K. R. Venugopal Reddy, and O. Nagaraja

Department of Studies and Research in Chemistry, Vijayanagara Sri Krishnadevaraya University, Ballari-583105, India

E-mail: mounesh.m.nayak@gmail.com

Received: 14 July 2020  Accepted: 29 January 2021

Abstract:

Here, we are reporting cobalt(II) phthalocyanine (CoPc) containing the active catalyst for the electrochemical investigations of bioanalytes. The synthesized tetra-n-octadecylcarboxamide cobalt(II) phthalocyanine was characterized by FT-IR, UV, TGA, mass and powder XRD analysis. In the present work, the synthesized complex was characterized by cyclic voltammetry and shows the redox behaviour corresponding to central metal (Co^+II/Co^+I) of the complex. Three biomolecules are well separated by their oxidation peaks in simultaneous detections of AA, DA and UA at 170, 350 and 550 mV with increasing high positive peak current. The low detection limit of AA, DA and UA was 40, 30 and 30 µmol by CV methods. The modified tetra substituted CoODAPc/GCE exhibits an excellent electrocatalytic activity, stability, high sensitivity, good linearity and selectivity without losing its catalytic activity and proves to be a versatile chemical sensor for commercial pharmaceutical samples, vitamin C tablets and dopamine injections.

Graphic abstract

Keywords: Sensors; Ascorbic acid; DCC; GCE; DA; UA; CoPc

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-021-01547-5

Chemical Papers 75 (6) 2945–2956 (2021)