ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Recent development in chemosensor probes for the detection and imaging of zinc ions: a systematic review

D. Sadananda, A. M. M. Mallikarjunaswamy, C. N. Prashantha, Ramanjaneyulu Mala, Kuruvalli Gouthami, Lavanya Lakshminarayana, Luiz Fernando Romanholo Ferreira, Muhammad Bilal, Abbas Rahdar, and Sikandar I. Mulla

WPU Division, Institute of Wood Science and Technology, Bangalore, India

E-mail: sikandar.mulla@gmail.com

Received: 14 September 2021  Accepted: 18 May 2022

Abstract:

Zinc is an essential and second most abundant transition element in the human body after the iron (Fe³⁺). Chemosensors have unique nature for detection of various selective metal ions [including Zinc (Zn²⁺ ion)]. On the other hand, zinc is required for a variety of biological activities and enzymatic reactions proceed in the human body. However, the presence of certain of them in the environment, such as cadmium, lead, mercury, and others, poses health concerns and dangers. Fluorescent imaging has been shown to be the best tool for in vivo monitoring of zinc, a vital biological element for all living things. Which are in cell death, gene expression control, brain signal transmission, pathogenic, and other physiological activities. However, the question of how quickly to detect Zn²⁺ in biology remains difficult and important. Using appropriate fluorescent chemosensors, here, we aim to highlight current developments in detecting and bioimaging physiologically, ecologically, and industrially relevant metal ion(s) such as Zn²⁺. Additionally, this review has given a brief account of various detection methods Zn²⁺ sensors such as an internal charge transfer, photo induced electron transfer, fluorescence resonance energy transfer, chelation-enhanced fluorescence, and the importance of fluorescent chemosensors and their photophysical properties. This review will helpful to environmental chemists.

Keywords: Zinc ion; Fluorescent chemosensors; Internal charge transfer; Photo induced electron transfer; Fluorescence resonance energy transfer

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-022-02284-z

Chemical Papers 76 (10) 5997–6015 (2022)