ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7

Published monthly

Synthesis, characterization, and in vitro antibacterial assays of a new mixed-ligand oxidovanadium (IV) complex

Tayebeh Zandevakili, S. Jamiladin Fatemi, S. Yousef Ebrahimipour, and Hadi Ebrahimnejad

Department of Chemistry, Faculty of Science, Shahid Bahonar University of Kerman, Kerman, Iran



Received: 19 June 2022  Accepted: 20 August 2022


A new mixed-ligand oxidovanadium (IV) complex, [VO(DFX)(1,10-phen)], in which DFX = Deferasirox and 1,10-phen = 1,10-phenanthroline, was synthesized using the reflux method and characterized by Fourier transform infrared spectroscopy (FT-IR), UV–Vis spectroscopy and field emission scanning electron microscopy (FE-SEM). Distorted octahedral geometry is suggested for the complex. The DFX ligand is coordinated to the central atom by two phenolate oxygen atoms and one triazole nitrogen atom. Two nitrogen atoms of the 1,10-phen ligand and the oxo group occupy three other positions around the central atom. The in vitro antibacterial activity of the synthesized complex, metal precursor (VO(acac)2) and parent ligands was evaluated against Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Pseudomonas aeruginosa bacterial strains. Furthermore, the antibiofilm activity of these compounds was investigated against S. aureus and P. aeruginosa bacteria. Based on the obtained results, the [VO(DFX)(1,10-phen)] complex exhibited higher antibacterial and antibiofilm activities in comparison to VO(acac)2, DFX and 1,10-phen.

Graphical abstract

Keywords: V(IV) complex; Antibacterial activity; Antibiofilm activity

Full paper is available at

DOI: 10.1007/s11696-022-02443-2


Chemical Papers 77 (2) 771–779 (2023)

Saturday, May 18, 2024

SCImago Journal Rank 2021
European Symposium on Analytical Spectrometry ESAS 2022
© 2024 Chemical Papers