ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7

Published monthly
 

Recent advances in transamidation of unactivated amides

Vishal Kumar, Sanjeev Dhawan, Renu Bala, Pankaj S. Girase, Parvesh Singh, and Rajshekhar Karpoormath

Department of Pharmaceutical Chemistry, Discipline of Pharmaceutical Sciences, College of Health Sciences, University of KwaZulu-Natal (Westville), Durban, South Africa

 

E-mail: Singhp4@ukzn.ac.za

Received: 12 May 2022  Accepted: 3 March 2023

Abstract:

In recent years, transamidation has been an essential topic in the formation of amide bonds over the conventional route due to chemoselectivity and greenside products. So many groups have disclosed new amide transformation techniques. Transamidation is typically classified into two categories based on amide activation: activated amide and unactivated amide. We conducted a review of the pertinent literature that discusses the cross amidation reactions of unactivated amides employing a variety of reagents, enabling contemporary research professionals to overcome synthetic barriers.

Graphical abstract

Keywords: Catalyst; N-Formylation; N-Acetylation; Transamidation; Unactivated amides

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-023-02772-w

 

Chemical Papers 77 (8) 4057–4084 (2023)

Monday, May 20, 2024

IMPACT FACTOR 2021
2.146
SCImago Journal Rank 2021
0.365
SEARCH
Advanced
VOLUMES
European Symposium on Analytical Spectrometry ESAS 2022
© 2024 Chemical Papers