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Biofabrication of copper oxide nanoparticles using Solanum tuberosum L. var. Vitelotte: characterization, antioxidant and antimicrobial activity

Gamze Topal Canbaz, Zehra Seba Keskin, Ahmet Yokuş, and Rukiye Aslan

Department of Chemical Engineering, Engineering Faculty, Sivas Cumhuriyet University, Sivas, Turkey



Received: 26 December 2022  Accepted: 10 March 2023


In this study, Solanum tuberosum L. var. Vitelotte extract and copper oxide nanoparticles (CuONPs) were synthesized for the first time by the green synthesis method, which is the cheapest and most effective method. The synthesized nanoparticles were analyzed by SEM, EDX, XRD, and FTIR. In the SEM analysis, the synthesized particles had a spherical morphology in the size range of 190–220 nm. In the EDX analysis, the amounts of Cu and O atoms forming the structure of the nanoparticles were determined as 66.77% and 31.75%, respectively. In XRD analysis, the crystal size of nanoparticles was calculated as 7.22 nm. The bonds that are effective in nanoparticle synthesis were identified by FTIR spectroscopy. The antibacterial activities of CuONPs obtained by green synthesis against gram-negative Escherichia coli and gram-positive Staphylococcus aureus were examined and determined that they had antibacterial effects against both bacteria. The antioxidant activity of CuONPs was also investigated on the basis of free radical scavenging activity by the DPPH method. The antioxidant capacities of Solanum tuberosum L. var. Vitelotte extract and CuONPs were determined in the range of 28–31% at 50–250 μg/mL concentrations, and over 80% activity was determined at 500 μg/mL concentration.

Keywords: CuONPs; Green synthesis; Antimicrobial; DPPH scavenging; Solanum tuberosum L. var. Vitelotte

Full paper is available at

DOI: 10.1007/s11696-023-02776-6


Chemical Papers 77 (8) 4277–4284 (2023)

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