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Optimization of ultrasonic-assisted ethanol extraction of polyphenols from Phyllanthus emblica by response surface methodology

Ya-Li Wu, Wei Zhang, Li-Da Guo, Su-Qing Zhang, and Shi-Zhong Liang

Department of Food, Guangdong Industry Technical College/Center of Guangdong Higher Education for Engineering and Technological Development of Speciality Condiments, Guangzhou, China



Received: 12 May 2023  Accepted: 5 September 2023


Polyphenols are indispensable as the main antioxidant substances of Phyllanthus emblica. In this study, ultrasonic-assisted extraction of emblic leafflower fruit polyphenol was performed with ethanol, and a response surface method was used to optimize the extraction results and determine parameters for the best conditions. These parameters included a drying temperature of 80 °C emblic leafflower fruit pulp, 60% alcohol concentration, solid‒liquid ratio, ultrasonic extraction time of 24 min and ultrasound temperature of 45 °C. Under the experimental conditions, the yield of polyphenols obtained from P. emballiae was 10.40%, which was almost the same as the ideal prediction value (10.39%). The established regression model shows a good fitting degree.

Keywords: Phyllanthus emblica polyphenols; Ultrasonic; Response surface methodology

Full paper is available at

DOI: 10.1007/s11696-023-03066-x


Chemical Papers 78 (1) 221–229 (2024)

Monday, May 27, 2024

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