ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Aniline-2,5-disulfonic acid based new proton transfer salt and new Co(II) and Cu(II) coordination polymers: synthesis, structural and antimicrobial studies

Nurgün Büyükkıdan, Seda Bozyel Turgut, Halil İlkimen, Musa Sarı, and Aysel Gülbandılar

Department of Chemistry, Faculty of Arts and Science, Kütahya Dumlupınar University, Kütahya, Türkiye

E-mail: nurgun.buyukkidan@dpu.edu.tr

Received: 20 March 2024  Accepted: 31 May 2024

Abstract:

The new salt named 4,4'-thiobis(pyridin-1-ium) aniline-2,5-disulfonate (1), (H₂DPS)²⁺(ADSA)²⁻ (1), was synthesized by the reaction of 1,2-di(pyridin-4-yl)disulfane (DPDS) and aniline-2,5-disulfonic acid (H₂ADSA) at reflux temperature. Also, new coordination polymers formulated as {[M(DPS)₂(H₂O)₂]}_n(ADSA)·4H₂O {DPS = di(pyridin-4-yl)sulphane, M = Co(II) (2) and Cu(II) (3)} were synthesized from the salt 1. The structure of 1 was clarified using methods such as elemental analysis, nuclear magnetic resonance, ultraviolet–visible and infrared spectroscopy. For the structural examinations of 2 and 3, magnetic susceptibility, spectroscopic analysis and an X-ray study were used. X-ray analysis showed that the DPS ligand coordinated to Co(II) in complex 2 and Cu(II) in complex 3. In both coordination polymers, the coordination sphere of the M(II) ion with six coordination numbers consists of four N atoms of four DPS molecules and two O atoms of two water molecules, resulting in a distorted octahedral geometry. Antibacterial properties were tested against Bacillus subtilis, Listeria monocytogenes (ATCC 7644), Staphylococcus aureus (NRRL B-767), Enterococcus faecalis (ATCC 29212), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922) and were tested against yeast Candida albicans (F89). The antibacterial activities of the compounds were compared with the control drugs Cefepime, Levofloxacin and Vancomycin and their antifungal activities were compared with the antifungal reference drug Fluconazole.

Keywords: Salt; Metal complexes; Aniline-2,5-disulfonic acid; Single crystal XRD; Antimicrobial

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-024-03544-w

Chemical Papers 78 (11) 6405–6416 (2024)