ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis, Characterization, and Antioxidative Activity of Ternary Rare-Earth Complexes of 5-Fluorouracil-1-acetic Acid and 2,2-Bipyridine

J. Huang, J. Q. Qu, L. F. Wang, Y. Q. Liu, Y. Y. Wang, and Y. M. Song

State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China

E-mail: qjqlw@hotmail.com

Received: 19 April 2004

Abstract: Seven new solid ternary complexes of 5-fluorouracil-1-acetic acid (HFAA) and 2,2 _ -bipyridine (Bipy) with rare-earth metals have been synthesized. Elemental analysis, molar conductivity, IR, TG-DTA, UV, and 1 H NMR spectra have been used to characterize these complexes. The general formula for the complexes is M(FAA) 3 Bipy · n H 2 O, where M = Y, La, Ce, Sm, Gd, Dy or Er, n = 0, 2 or 5. The antioxidative activity of these complexes was tested. The results obtained showed that the suppression ratios of these complexes for O . − 2 free radical are mostly higher than those of HFAA and Bipy.

Full paper in Portable Document Format: 594a267.pdf

Chemical Papers 59 (4) 267–270 (2005)