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A Kinetic Model for Gluconic Acid Production by Aspergillus niger

H. Znad, M. Blažej, V. Báleš, and J. Markoš

Department of Chemical and Biochemical Engineering, Faculty of Chemical and Food Technology, Slovak University of Technology, SK-812 37 Bratislava



Received: 10 April 2003

Abstract: Fermentation kinetics of gluconic acid production by Aspergillus niger was studied in a batch system. The dependence of the specific growth rate on carbon and oxygen substrates was assumed to follow either the Monod or Contois kinetic model. The simulation results revealed that for predicting the fermentation process of gluconic acid production by A. niger, the Contois typemodel was more suitable than that based on the Monod equation. The Luedeking|Piret equation was proposed for gluconic acid production and an equation considering the cell maintenance for glucose and dissolved oxygen consumption. Estimated parameters of this model indicate that the production of gluconic acid was mostly growth-associated.

Full paper in Portable Document Format: 581a23.pdf


Chemical Papers 58 (1) 23–28 (2004)

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