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Synthesis and Enzymic Effect of Some Novel 1,2-Dihydro-3-(triazin-5/6-yl)benzo[h]quinolin-2-one Derivatives

M. M. Ismail

Department of Chemistry, Faculty of Education, Ain Shams University, Roxy 11711, Cairo, Egypt

 

E-mail: mmismail@chemist.com

Abstract: Some 3-(triazin-5/6-yl)quinolinones were obtained starting with benzoquinolylglyoxal. Hydrazinolysis of these triazines furnished hydrazinotriazines. The latter compounds were cyclized to give some triazolo/tetrazolotriazinylquinolin-2-ones. Reaction of hydrazinotriazines with formylquinoline and quinolinyl β-keto ester gave the corresponding hydrazones, which were consequently cyclized to pyrazole derivatives. All the newly prepared compounds revealed potent effect on increasing reactivity of cellobiase.

Full paper in Portable Document Format: 554a242.pdf

 

Chemical Papers 55 (4) 242–250 (2001)

Tuesday, May 28, 2024

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