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Simple Synthesis of Some Diphenylsulfapyrimidine Acetates from Chalcones and their Antimicrobial Activity

A. A. F. Wasfy and A. A. Aly

Department of Chemistry, Faculty of Science, Benha University, Benha, Egypt

 

E-mail: wasfy588@hotmail.com

Received: 14 August 2002

Abstract: Since a very low yield (19—43 %) in the reported results on the cyclocondensation of sulfaguanidine acetate with chalcones was given, a careful reinvestigation was carried out. New series of chalcones, bearing electron-attracting groups in the aromatic moiety, have been used as precursors in the synthesis of diphenylsulfapyrimidine acetates with good yield. The compounds were tested for their biological properties.

Full paper in Portable Document Format: 575a364.pdf

 

Chemical Papers 57 (5) 364–368 (2003)

Tuesday, May 21, 2024

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