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Synthesis of Furyl-Substituted Isoxazoles, Isoxazolines, and 1,2,4-Oxadiazoles

E. Jedlovská and Ľ. Fišera

Department of Organic Chemistry, Faculty of Chemical Technology, Shvak Technical University, CS-812 37 Bratislava

 

Abstract: The synthesis of 3,5-disubstituted isoxazoles, isoxazolines, and 1,2,4-oxadiazoles by 1,3-dipolar cycloaddition of 5-X-2-furonitrile oxides (X = 4-, 3-, 2-nitrophenyl or nitro group) with phenylacetylene, propargyl bromide, styrene, allyl alcohol, allyl bromide, and N-cyanoguanidine is described.

Full paper in Portable Document Format: 461a42.pdf

 

Chemical Papers 46 (1) 42–46 (1992)

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