ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Kojic acid derivatives. 1. Preparation and bromination of some 5-hydroxy-2-(R-thiomethyl)-4H-pyran-4-ones

R. Sandtnerová and M. Koóš

Institute of Chemistry, Slovak Academy of Sciences, CS-84238 Bratislava

Abstract: By the reaction of chlorokojic acid with some sodium thiolates, 5-hydroxy-2-(R-thiomethyl)-4H-pyran-4-ones were prepared. Bromination of these compounds using N-bromosuccinimide afforded corresponding 6-bromo derivatives. The structure of the prepared pyranones was proved by IR, ¹H NMR, ¹³C NMR, and mass spectral data. Their antimicrobial activity was also determined.

Full paper in Portable Document Format: 454a559.pdf

Chemical Papers 45 (4) 559–565 (1991)