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Synthesis and antimicrobial activity of some 5-substituted 7-tetrazolylacetamido-3-acetoxycephalosporanic acids and their sodium salts

Ľ. Janda and Z. Votický

Drug Research Institute, CS-900 01 Modra

 

Abstract: 5-Substituted 7-(1-resp. 2-tetrazolylacetamido)-3-acetoxycephalosporanic acids and their sodium salts were obtained by TV-acylation of 7-ami­nocephalosporanic acid with reactive derivatives of 5-substituted 1- resp. 2-tetrazolylacetic acids. The final products were tested against Gram-posi­tive and Gram-negative strains of microorganisms.

Full paper in Portable Document Format: 431a77.pdf

 

Chemical Papers 43 (1) 77–86 (1989)

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