|
|
ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Published monthly
|
Retention indexes of some ß-adrenolytics and their perfluoroacyl derivatives
V. Marko
Institute of Experimental Pharmacology, Centre of Physiological Sciences,
Slovak Academy of Sciences, CS-842 16 Bratislava
Abstract: Retention indices (RI) of 10 ß-adrenolytics and their trifluoroacetyl and
heptafluorobutyryl derivatives on columns with nonpolar OV1 and
moderately polar OV 17 stationary phases, respectively, have been studied.
The retention indices of the original drugs on the OV 1 phase ranged from
1721 to 2795 and on the OV 17 phase from 1939 to 3290. By derivatization
the differences in RI values in the systems with different stationary phases
decreased and so did the differences in values obtained in different laborato
ries.
Full paper in Portable Document Format: 423a375.pdf
Chemical Papers 42 (3) 375–380 (1988)
|