ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7

Published monthly
 

Claisen condensation of dimethyl 2,3-thiophenedicarboxylate with methyl acetate and acetonitrile

M. Struhárik and P. Hrnčiar

Department of Organic Chemistry, Faculty of Natural Sciences, Komenský University, CS-S42 15 Bratislava

 

Abstract: Claisen condensation of dimethyl 2,3-thiophenedicarboxylate with methyl acetate has been carried out. It was found that practically only the first step of the reaction proceeded on the carbon of the methoxycarbonyl group in the position 2 of the thiophene ring, while 4,5-dihydro-6H-cycIopenta[/?]thiophe- ne-4,6-dione (II) was formed only in a low yield. Higher yields of ß-diketone (II) were not achieved by changing the reaction conditions. Also the reaction with acetonitrile proceeded on the carbon of the methoxycarbonyl group in the position 2 of the thiophene ring and the cyclic product has not been isolated. The compounds obtained were characterized by their IR, 'H NMR, and n C NMR spectra.

Full paper in Portable Document Format: 393a391.pdf

 

Chemical Papers 39 (3) 391–400 (1985)

Thursday, September 29, 2022

IMPACT FACTOR 2021
2.146
SCImago Journal Rank 2021
0.365
SEARCH
Advanced
VOLUMES
European Symposium on Analytical Spectrometry ESAS 2022
© 2022 Chemical Papers