ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
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Synthesis and Antimicrobial Activity of

A. I. El-Shenawy

Department of Chemistry, Faculty of Science, Benha University, Benha, Egypt


E-mail: ref

Received: 14 October 2003

Abstract: Epoxide derivative II was used to synthesize a number of new condensed and noncondensed heterocyclic systems. Thus, reaction of II with amines, hydrazines, active methylene compounds and Friedel—Crafts reactions have been studied. On the other hand, II reacted with Grignard reagents and afforded products with an open epoxide ring. However, II condensed with thiourea and glycine gave oxazolinethione and 2-morpholinone derivatives. Also, II reacted with acetic acid and gave hydroxypropanoyl derivative. Action of different nitriles with II gave the hydroxy amide derivatives, which underwent cyclization and afforded 2-oxazoline derivatives.

Full paper in Portable Document Format: 593a196.pdf


Chemical Papers 59 (3) 196–201 (2005)

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