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Preparation and biological activity of substituted 1-[2-(alkylthio)-6-benzothiazolylaminomethyl]-5-phenyl-1,2,3,4-tetrazoles

E. Holbová and M. Uher

Institute of Chemistry, Komenský University, 842 15 Bratislava

 

Abstract:  By Mannich reaction of 6-amino-2-R-thiobenzothiazoles with formaldehyde and 5-(R1phenyl)-1,2,3,4-tetrazoles, 1-(2-alkyl-, -aryl-, and -benzylthio-6-benzothiazolylaminomethyl) derivatives of substituted tetrazoles have been prepared. The highest biological activity has been found with 2-ethyl deriva­tives of the prepared compounds.

Full paper in Portable Document Format: 362a253.pdf

 

Chemical Papers 36 (2) 253–257 (1982)

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