ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Structure elucidation of new N-aminoacetyl-o-alkoxymethylanilide type local anesthetics by mass spectrometry

M. Štefek, L. Beneš, and V. Kováčik

Institute of Experimental Pharmacology, Slovak Academy of Sciences, 881 05 Bratislava

Abstract:  Electron impact mass spectra of several newly synthesized aminoacetylanilide type substances have been studied. Using labelling experiment, metastable transition measurements, and high-resolution mass spectrometry, the fragmentation mechanisms of the substances of this class have been elucidated. The information thus obtained is discussed from the point of view of the determination of structure of substances of this type.

Full paper in Portable Document Format: 344a543.pdf

Chemical Papers 34 (4) 543–549 (1980)