ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis of 5-(4-Y-benzyl)-1,3-thiazolidine-2-thiones and 5-(4-Y-benzyl)-1,3-selenoazolidine-2-thiones

J. Bernát and M. Cigániková

Department of Organic Chemistry, Faculty of Natural Sciences, P. J. Šafárik University, 041 67 Košice

Abstract: Sodium hydrogen sulfide and selenide react with 2-chloro-3-(4-Y-phenyl)-propyl isothiocyanates and phenylallyl isothiocyanate to yield sodium salts of dithiocarbamate and selenothiocarbamate which, upon acidification with dilute hydrochloric acid, undergo an intramolecular cyclization under formation of 5-(4-Y-benzyl)-1,3-thiazolidine-2-thiones and their selenium analogues. The structure of products was deduced from ¹H-n.m.r., i.r., and Raman spectra.

Full paper in Portable Document Format: 335a663.pdf

Chemical Papers 33 (5) 663–668 (1979)