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Furan derivatives. CI. Nitration of methyl 2-cyano-3-R-3-(2-furyl)acrylates and some properties of their nitro derivatives

M. Černayová, J. Kováč, M. Dandárová, P. Foltínová, and L. Ebringer

Department of Organic Chemistry, Slovak Technical University, 880 37 Bratislava

 

Abstract: Nitration of methyl 2-cyano-3-R-3-(2-furyl)acrylates (R = CH3 , C2H5, n-C3H7, i-C3H7 , n-C4H9 , i-C4H9, phenyl, 2-thienyl) and conformational analysis by means of 'H-n.m.r. spectrometry of the formed 5-nitrofuryl derivatives is described. The effect of the substituents upon the biological properties of the substances under investigation is discussed on the basis of antimicrobial tests.

Full paper in Portable Document Format: 323a378.pdf

 

Chemical Papers 32 (3) 378–385 (1978)

Monday, June 24, 2024

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