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ISSN electronic edition: 1336-9075
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Benzothiazole compounds. III. Synthesis and biological activity of substituted N-(2-benzothiazolyl)ureas and benzothiazolyldihydrouracils

V. Sutoris and J. Halgaš

Department of Organic Chemistry and Biochemistry, Faculty of Natural Sciences, Komenský University. 801 00 Bratislava

 

Abstract: N-(4-X-6-X1-2-Benzothiazolyl)-N'-( β-bromopropionyl)ureas were prepared by treatment of 4,6-substituted 2-aminobenzothiazoles with ß-bromopropionyl isocyanate and converted to cyclic 1-(4-X-6-X1-2-benzotliiazolyl)dihydrouracils. Antibacterial, antifungal, and antiprotozoal effects in vitro were observed with the described compounds.

Full paper in Portable Document Format: 276a829.pdf

 

Chemical Papers 27 (6) 829–833 (1973)

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