ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

The polysaccharides of yeasts. II. The extracellular mannans of Candida albicans

D. Šikl, L. Masler, and Š. Bauer

Institute of Chemistry, Slovak Academy of Sciences, Department of Biochemistry of Saccharides, Bratislava

Abstract: In the culture liquid from the cultivation of five strains of Candida albicans BERKHOUT on the glucose substrate the high branching extracellular α-mannans of DP 150—630 were isolated. The extracellular mannans belong to two structural types as on the base of methylation analysis, partial hydrolysis, periodate oxidation and Smith degradation was found out. The first one, less branched has the main linkage composed from mannose units linked through α-1,6 glycosidic linkages. To every second mannose unit two to five-unit side chains containing α-1,2 glycosidic linkages are attached. The side chains are bound to main chain with α-1,2 linkage. In the second more branched type every unit of main chain is the branching point, where the four-unit side chains through α-1,2 glycosidic linkages are attached. In the main chains α-1,6 linkages, in the side chains α-1,2 linkages are present.

Full paper in Portable Document Format: 211-2a3.pdf

Chemical Papers 21 (1-2) 3–12 (1967)