ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

A New Method of Labelling Rose Bengal with ¹³¹I and ¹²⁵I

P. Raban and V. Gregora

Institute of Biophysics, Faculty of General Medicine, Charles" University, Prague

Abstract: Differences in the composition of rose bengal influence the results of liver chromoexcretion tests. Preparation of pure rose bengal, i. e. tetraiodotetrachlorofluorescein (TITCF) and its labelling with ¹³¹I and ¹²⁵I  in a suitable medium is discussed. Yields of the exchange reaction between non-radioactive TITCF and radioactive elementary iodine in ethanol—ether solution are good. Dependencies of radiochemical yield and radiochemical purity on reaction time and temperature are established. The dependence of radiochemical yield on concentration of elementary iodine is evaluated.

Full paper in Portable Document Format: 218a586.pdf

Chemical Papers 21 (8) 586–591 (1967)