ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Mild and efficient conversion of trifluoromethylarenes into tribromomethylarenes using boron tribromide
Hongbiao Chen, Jianxiang Yin, and Yuanbin Lin
Chemistry College, Xiangtan University, Xiangtan, 411105, Hunan Province, China
Received: 5 February 2008 Revised: 27 June 2008 Accepted: 4 July 2008
Abstract: Tribromomethylarenes were prepared efficiently, at room temperature, from trifluoromethylarenes with boron tribromide as the
brominating reagent. The present process is applicable to the preparation of various substituted benzotribromide derivatives
from substituted benzotrifluoride compounds. p-Substituted benzotrifluoride compounds were found to be more reactive than o-substituted isomers under the given reaction conditions.
Keywords: trifluoromethylarenes - tribromomethylarenes - tribromomethylation - substitution reaction - boron tribromide
Full paper is available at www.springerlink.com.
Chemical Papers 63 (1) 92–96 (2009)