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Oscillopolarographic determination of thalidomide

J. S. Hetman

C/o Dr. A. Kuntze, Elektronische Analysengeräte, Düsseldorf—Oberkassel, Germany.

 

Abstract: An oscillopolarographic detn. of thalidomide (Contergan) in a supporting electrolyte contg. 0.1 M barbitone, 40.0% MeOH, and 0.1M LiCl was described. Thalidomide produced on the curve of the function dE/dt = f(E) an irreversible cathodic incision at the Q value 0.66. Thalidomide can be detd. at concns. as low as 2 γ/ml. with no interference from SO4-, NO3-, NO2-, Cl-, or Br-. Zn produced a discontinuity at the same potential as thalidomide.

Full paper in Portable Document Format: 185-6a422.pdf (in German)

 

Chemical Papers 18 (5-6) 422–424 (1964)

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