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Synthesis, characterization, and antimicrobial activity of new benzoylthiourea ligands

Gülşah Kurt, Fatih Sevgi, and Bedrettin Mercimek

Department of Chemistry, Faculty of Education, Selçuk University, Meram, 42099 Konya, Turkey

 

E-mail: g_kurt_81@hotmail.com

Received: 1 December 2008  Revised: 20 January 2009  Accepted: 26 January 2009

Abstract: In this study, new benzoylthiourea derivatives, (E)-N-[(2-benzamidomethyleneamino)ethylcarbamothioyl]benzamide H3L′, N-(1-(3-benzoylthioureido)propan-2-ylcarbamothioyl)-benzamide H4L″, (E)-N-[4-(benzamidomethyleneamino)phenylcarbamothioyl]benzamide H3L‴, were synthesized. Structures of the compounds were identified by spectroscopic techniques. In addition, all synthesized compounds were evaluated for in vitro antibacterial and antifungal activity. Compound H3L‴ exhibited antibacterial activity.

Keywords: benzoylthiourea - antimicrobial activity - thermal properties - SEM - synthesis

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-009-0055-1

 

Chemical Papers 63 (5) 548–553 (2009)

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