ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Three-component one-pot reaction for the synthesis of β-amide ketones
Yan-Ping Luo and Qiong Chen
Key Laboratory of Protection and Development Utilisation of Tropical Crop Germplasm Resources, Hainan University, Ministry of Education, HaiKou, 570228, China
Abstract: β-amide ketones were synthesised by a three-component one-pot reaction of phenylacetylene, aldehydes, and amides in anhydrous acetonitrile containing trifluoroacetic acid and acetic acid in the presence of AlCl3 catalyst. The title compound structures were identified by 1H NMR, 13C NMR, MS, and elemental analysis.
Keywords: β-amide ketones – one-pot reaction – synthesis
Full paper is available at www.springerlink.com.
Chemical Papers 67 (5) 532–537 (2013)
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