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Novel benzopyranopyridine derivatives of 2-amino-3-formylchromone

Zeba Nafees Siddiqui, Shagufta Praveen, and Farheen Farooq

Department of Chemistry, Aligarh Muslim University, Aligarh, 202002 India

 

E-mail: zns.siddiqui@gmail.com

Abstract: Enol lactones such as 4-hydroxy-6-methyl-2H-pyran-2-one (triacetic acid lactone, TAL) and 4-hydroxycoumarin when treated with 2-amino-3-formylchromone under basic conditions afforded 3-acetoacetyl benzopyranopyridones and benzopyranopyridines, respectively. A series of pyrazole derivatives was prepared by the reaction of 3-acetoacetyl benzopyranopyridones with different hydrazines. All compounds were characterised on the basis of spectral data and their antibacterial activity evaluated.

Keywords: 2-amino-3-formylchromone - 4-hydroxycoumarin - pyranopyridines - antibacterial

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-010-0072-0

 

Chemical Papers 64 (6) 818–824 (2010)

Thursday, August 18, 2022

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