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A simple procedure for the synthesis of novel 3-(benzofur-2-yl)pyrazole-based heterocycles

Mohammed A. Baashen, Bakr F. Abdel-Wahab, and Gamal A. El-Hiti

Shaqra University, Duwadimi, Saudi Arabia

 

E-mail: balshobia@su.edu.sa

Abstract: 3-(Benzofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde was used, as a precursor for the synthesis of a series of novel heterocycles by facile reactions with 3-oxo-3-phenylpropanenitrile, 2-cyanoethanethioamide, and various hydrazides such as cyanoacetohydrazide, acetohydrazide, and carbohydrazide derivatives. The structures of the products were confirmed by various spectroscopic methods along with the X-ray crystal structures.

Keywords: 2-Substituted benzofuran; Pyrazole-4-carbaldehyde; Carbohydrazide; Heterocycles; Synthesis

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-017-0209-5

 

Chemical Papers 71 (11) 2159–2166 (2017)

Thursday, August 18, 2022

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