ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
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Nanoencapsulation strategies for lipid-soluble vitamins

Shubham Subrot Panigrahi, Irshaan Syed, Sivapratha Sivabalan, and Preetam Sarkar

National Institute of Technology Rourkela, Rourkela, India



Abstract: Functional properties of liposoluble vitamins have been extensively used in the food industry for the development of nutrition-based products. But their efficacy tends to decline because of oxidation reactions as they are highly sensitive to free radicals and other metallic ions. In addition, lipid-soluble vitamins also demonstrate limited water solubility. Thus, dissolution in aqueous-based foods is a challenge. Some techniques have been suggested for the protection of lipid-soluble vitamins. One such method is nanoencapsulation which has recently posed a novel platform for showing enhanced bioavailability, higher shelf life and controlled release of entrapped liposoluble vitamins. In this work, we focus on five model lipid-based nanodelivery systems: (1) conventional nanoemulsions, (2) nanoliposomes, (3) solid lipid nanoparticles, (4) nanostructured lipid carriers and (5) nanosuspensions. First, we focus on the specific liquid and electrochemical techniques available for the preparation of such nanostructures. In the next phase, the five different lipid-based nanostructures have been discussed with their formulation techniques (energy and pressure attributes) concerning their encapsulation strategy for lipid-soluble vitamins.

Keywords: Nanoemulsions ; Nanoliposomes ; Nanosuspensions ; Solid lipid nanoparticles 

Full paper is available at

DOI: 10.1007/s11696-018-0559-7


Chemical Papers 73 (1) 1–16 (2019)

Tuesday, May 28, 2024

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