ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Voltammetric sensing of minoxidil using a molecularly imprinted polymer (MIP)-modified carbon paste electrode

Sara Dehdashtian and Beshare Hashemi

Shohadaye Hoveizeh University of Technology, Susangerd, Iran

E-mail: saradehdashtian@yahoo.com

Abstract: This study presents voltammetric sensing of minoxidil using a molecularly imprinted polymer (MIP). For fabrication of the electrochemical sensor, the synthesized MIP was incorporated into the carbon paste electrode (CPE). MIP-CPE and non-imprinted polymer carbon paste electrode were compared for the recognition ability toward minoxidil. The most important parameters affecting sensor performance were optimized and a calibration curve was then plotted using differential pulse voltammetric technique. Under optimum conditions, the sensor has a linear response in the 1–400 nM minoxidil concentration range and a 0.3 nM limit of detection (at an S/N ratio of 3). Also, the selectivity of the sensor was investigated. Finally, this sensor was applied successfully for minoxidil determination in real samples with different matrices.

Keywords: Molecularly imprinted polymer (MIP) ; Voltammetric sensing ; Minoxidil 

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-019-00860-4

Chemical Papers 74 (1) 157–165 (2020)