ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis, characterization, and antimicrobial activity of new benzoylthiourea ligands

Gülşah Kurt, Fatih Sevgi, and Bedrettin Mercimek

Department of Chemistry, Faculty of Education, Selçuk University, Meram, 42099 Konya, Turkey

E-mail: g_kurt_81@hotmail.com

Received: 1 December 2008  Revised: 20 January 2009  Accepted: 26 January 2009

Abstract: In this study, new benzoylthiourea derivatives, (E)-N-[(2-benzamidomethyleneamino)ethylcarbamothioyl]benzamide H₃L′, N-(1-(3-benzoylthioureido)propan-2-ylcarbamothioyl)-benzamide H₄L″, (E)-N-[4-(benzamidomethyleneamino)phenylcarbamothioyl]benzamide H₃L‴, were synthesized. Structures of the compounds were identified by spectroscopic techniques. In addition, all synthesized compounds were evaluated for in vitro antibacterial and antifungal activity. Compound H₃L‴ exhibited antibacterial activity.

Keywords: benzoylthiourea - antimicrobial activity - thermal properties - SEM - synthesis

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-009-0055-1

Chemical Papers 63 (5) 548–553 (2009)