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ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
Published monthly
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Palladium-catalyzed C(sp3)-C(sp2) coupling: synthesis of C(3)-arylphthalides
H. Surya Prakash Rao and J. Prabhakaran
Department of Chemistry, Pondicherry University, Puducherry, India
E-mail: hspr@teaduspharma.com
Received: 12 February 2024 Accepted: 15 May 2024
Abstract: We have achieved an efficient synthesis of C(3)-arylphthalides by coupling C(3)-bromophthalides and arylboronic acids under palladium catalysis. The C(sp3)-C(sp2) coupling worked well in the presence of water to provide products in a high yield. Graphical Abstract
Keywords: Arylphthalides; Suzuki coupling; Palladium; Coupling reactions
Full paper is available at www.springerlink.com.
DOI: 10.1007/s11696-024-03520-4
Chemical Papers 78 (10) 5985–5991 (2024)
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