ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Harnessing DABCO ionic salts for synthesis of heterocycles via multi-component reactions

Archana Rajmane, Poonam Narande, Nita Patil, and Arjun Kumbhar

Department of Chemistry, Vivekanand College, Kolhapur (An Empowered Autonomous Institute), Kolhapur, India

E-mail: arjun22win@rediffmail.com

Received: 30 July 2024  Accepted: 2 May 2025

Abstract:

The review article discusses the advancements in synthesis and applications of acidic, basic, and neutral 1,4-diazabicyclo[2.2.2]octane (DABCO) ionic salts in multi-component reactions. Compared to imidazolium-based ionic salts, the number of DABCO-based ionic salts is significantly lower. Recently, there has been increasing focus on these salts due to their selective salt formation capabilities. A significant challenge lies in the limited availability of physical data regarding DABCO-based ionic salts; hence, most of them are not ionic liquids. While many of these salts could be reused several times with only a minimal reduction in their catalytic effectiveness, there is a significant limitation in the availability of DABCO-based salts.

Graphical abstract

Keywords: 1,4-Diazabicyclo[2.2.2]octane; Ionic salts; Multi-component reactions; Recyclability

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-025-04189-z

Chemical Papers 79 (9) 5625–5660 (2025)