ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Smartphone-assisted biosensors in point-of-care diagnostics: integration, applications, and future challenges

Haluk Çelik, Balım Bengisu Caf, and Gizem Çebi

Vivosens, Inc., San Francisco, USA

E-mail: haluk.celik@stu.istinye.edu.tr

Abstract:

Point-of-care (POC) diagnostics is being revolutionized by smartphone-assisted biosensors, which combine cutting-edge sensing technologies with the computing power and connectivity of smartphones. These biosensors provide a portable and affordable substitute for conventional laboratory-based diagnostics by enabling the quick, real-time analysis of physiological parameters and biomarkers. Smartphone-assisted biosensors enable continuous health monitoring, enhanced patient engagement, and early disease detection by utilizing optical, electrochemical, and biomarker-based detection techniques. The development of smartphone-assisted biosensing platforms is reviewed in this article, along with their technological integration, detection methods, and medical applications. Sensor accuracy, data security, regulatory approval, and standardization continue to be challenges despite the progress. The impact of recent advancements on infectious disease management, chronic disease monitoring, and personalized medicine is highlighted in this review, which critically assesses wearable biosensors, AI-driven analytics, and smartphone-integrated disease detection systems.

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-025-04319-7

Chemical Papers 79 (11) 7323–7342 (2025)