ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Redox Behaviour of Some Superoxide Dismutase-Mimetic Copper(ll) Complexes of  N-Salicylideneaminoalkanoate Type with Diazoles

L. Andrezálová, J. Labuda, Z. Ďuračková, A. Valent, and F. Devínsky

Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, SK-832 32 Bratislava

Abstract: Eight copper(ll) complexes with a tridentate Schiff base and diazoles such as pyrazole, imidazole, and 3,5-dimethylpyrazole have been investigated voltammetrically at a hanging mercury drop electrode in phosphate buffer of pH 7.4. The complexes undergo a reversible one-electron reduction followed by the dissociation of the copper(I) compounds at a slow scan rate. The half-wave potential and rate constant data are reported and discussed with a superoxide dismutase-like activity of the complexes.

Full paper in Portable Document Format: 491a24.pdf

Chemical Papers 49 (1) 24–27 (1995)