ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis and reactivity of enamines in pyridine series

M. Bencková, D. Végh, J. Kováč, and Z. Friedl

Department of Organic Chemistry, Faculty of Chemical Technology, Slovak Technical University, CS-812 37 Bratislava

Abstract: The paper describes synthesis of enamines, containing substituted pyr­idine moiety at the double bond, by the reaction of suitably substituted picolines, lutidines, and collidines with dimethylformamide dimethyl acetal. By the same method enamino ketones derived from acetylpyridines were prepared. Rotational barriers of enamino ketones were measured by dynam­ic ¹H NMR spectroscopy. Enamino ketones were cyclized with hydrazine and cyanoacetamide.

Full paper in Portable Document Format: 431a51.pdf

Chemical Papers 43 (1) 51–61 (1989)