ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Isothiocyanates. II. The preparation of some thiocyanates derived from cancerogenic and cytostatic matter

P. Kristián, A. Hulka, K. Antoš, P. Nemec, and Ľ. Drobnica

Slovak Technical University, Bratislava

Abstract: cf. C.A. 53, 14979h. 4-[Bis(β-chloroethyl)amino]phenyl isothiocyanate, m. 85-6°, and 2-fluorenyl isothiocyanate, m. 107°, were prepd. in order to obtain compds. with a specific effect on nuclear matter. Because of easy oxidn. it was not possible to prep. from 2-[bis(β-chloroethyl)amino]-p-toluidine the corresponding isothiocyanate but some new intermediary products were prepd.: N,N-bis(β-hydroxyethyl)-4-nitro-ο-toluidine, m. 112-13°; N,N-bis(β-chloroethyl)-4-nitro-ο-toluidine, m. 65-6°, and 2-[bis(β-chloroethyl)amino]-p-toluidine, m. 88-9°.

Full paper in Portable Document Format: 132a103.pdf (in Slovak)

Chemical Papers 13 (2) 103–107 (1959)