ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis and spectroscopic characterisation of (E)-2-(2-(9-(4-(1H-1,2,4-triazol-1-yl)butyl)-9H-carbazol-3-yl)vinyl)-3-ethylbenzo[d]thiazol-3-ium, a new ligand and potential DNA intercalator

Agata Głuszyńska, Ewa Rajczak, and Bernard Juskowiak

Laboratory of Bioanalytical Chemistry, Faculty of Chemistry, A. Mickiewicz University, Umultowska Str. 89b, 61-614, Poznań, Poland

E-mail: aglusz@amu.edu.pl

Abstract: Three new compounds based on carbazole planar skeleton were synthesised. Among them there is a new ligand and a potential DNA intercalator which contains a benzothiazolium moiety connected to the carbazole ring by a vinyl bridge. The absorption and emission spectral properties of this new ligand have been studied by spectroscopic methods.

Keywords: carbazole derivative – UV-VIS absorption spectra – fluorescence – G-quadruplexes – DNA

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-013-0343-7

Chemical Papers 67 (9) 1231–1239 (2013)